Fig. 1
From: Transcriptomic profiling of skeletal muscle in the DMDmdx rat model of Duchenne muscular dystrophy
Histopathological features in the biceps femoris muscle of DMDmdx and WT rats: A) multifocal necrosis of myofibers (asterisk) and inflammatory infiltrates with a predominance of mononuclear cells (arrows), DMDmdx, H&E stain, 400x; B) satellite cells at the periphery of myofibers (arrows) in DMDmdx rat, indicating myofiber regeneration, H&E stain, 400x; C) marked variation in myofiber size, DMDmdx, H&E stain, 400x; D) interstitial hyperplasia of fibrous connective tissue (arrows) in DMDmdx, PSR stain, 100x; E) normal muscle fibers of WT, H&E stain, 100x, F) normal wild-type muscle of WT, PSR stain, 100x. DMDmdx – Sprague-Dawley DMDmdx rats; WT – Sprague-Dawley wild-type rats; H&E – hematoxylin and eosin; PSR – Picrosirius red.
