Fig. 7

Relative gene expression analysis in gastric CSCs treated with DSBCl. qPCR analysis of AGS and KATO III CSCs treated with the IC25 and IC50 of DSBCl. The bar graphs show the fold changes in genes involved in tumorigenesis, chemoresistance, and metastasis: NANOG, OCT4, MYC, KLF4, KLF17, BCL2L1, ABCC2, BAX, and ID1 in AGS CSCs (A) and BCL2L1, ABCC2, BAX, MYC, and ID1 in KATO III CSCs (B). Gene expression was normalized to that of the TBP and RPL29 housekeeping genes. Statistical significance: *p < 0.05; **p < 0.01; ***p < 0.001; ns not significant.