Fig. 1 | Scientific Reports

Fig. 1

From: miR-221 activates Sox11 to reduce brain injury after intracerebral hemorrhage via inhibiting neuroinflammation

Fig. 1

The expression level of Sox11 increased after intracerebral hemorrhage. (A) Western blot analysis showed that Sox11 protein levels gradually rise and peak at 24 h after ICH. (B) Quantitative analysis of the protein levels of Sox11 which were normalized to the mean value of that in the Sham group. (C) Double-immunofluorescence analysis was performed with antibodies against Sox11 and NeuN (neuronal marker). The nuclei were fluorescently labeled with DAPI. Arrows point to Sox11-positive neurons. Scale bar = 20 μm. (D) Quantification of the relative fluorescence intensities. (E) qPCR shown that the relative expression level of miR-221 changed after ICH. **P < 0.01 compared with the Sham group. All values are expressed as mean ± SD, n = 6.

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