Fig. 5 | Scientific Reports

Fig. 5

From: miR-221 activates Sox11 to reduce brain injury after intracerebral hemorrhage via inhibiting neuroinflammation

Fig. 5

The protective effect of Sox11 on behavioral/cognitive dysfunction testing in the rat after ICH. (A) Representative images of swimming trajectories on day 34 was shown. (B) Motor learning was assessed by the escape latency (time, s). (C) Spatial learning was assessed by the length of the swimming track of each rat. (D) Motor ability is assessed by time spent on the rotating stick. (E) The assessment of sensory ability was conducted by measuring the time required to remove the sticker. (F) Balance is evaluated based on the ratio of errors made. (G) The neurological scores of rats in each group. ICH group compared with the Sham group; ICH + mic-miR-221 group compared with the ICH + Vector group; ICH + Si-Sox11 group compared with the ICH + Si-Control group; **P < 0.01 and *P < 0.05. All data are expressed as mean ± SD, n = 6.

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