Fig. 10 | Scientific Reports

Fig. 10

From: Flecainide mediated sodium channel blockade enhances blood brain barrier integrity and promotes neuroprotection in neuroinflammation

Fig. 10The alternative text for this image may have been generated using AI.

Flow cytometric analysis of lymphocyte activation, adhesion, and proliferation markers after flecainide treatment. Splenocytes from mice treated with vehicle, 2 µM, or 5 µM flecainide were stimulated with CD3/CD28 antibodies and analyzed for expression of the proliferation marker Ki-67 (A), adhesion molecules CD11a (B) and CD49d (C), and activation markers CD25 (D) and CD69 (E) within CD3⁺, CD4⁺, CD8⁺, and CD19⁺ cell populations. No significant differences were observed between treatment groups. Bars represent mean ± SD. n = 5 mice per group.

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