Fig. 7 | Scientific Reports

Fig. 7

From: Flecainide mediated sodium channel blockade enhances blood brain barrier integrity and promotes neuroprotection in neuroinflammation

Fig. 7The alternative text for this image may have been generated using AI.

Analysis of Blood–Brain Barrier permeability using Evan’s Blue Assay after EAE Induction shows beneficial effects of flecainide. Quantitative data (A) and representative images (B) depict Evan’s Blue (EB) absorption at 565 nm from mice whole brains homogenate after weight correction, sacrificed at day 18 post-EAE induction at the peak of disease. Statistical significance is represented by *p < 0.05 and ns (not significant), determined by ANOVA followed by Dunnett’s post hoc test comparing to untreated MOG EAE mice. N = 15 per group. Scale bar: 2mm.

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