Table 1 Characteristics of NHANES samples (2007–2018).

From: Gender-specific associations of metabolic and circadian syndromes with melanoma risk: insights from NHANES 2007–2018

 

Total

N = 29,132

Non-melanoma

N = 28,923

Melanoma

N = 209

p

Age (years) (median (IQR))

45.00 (26.00)

45.00 (26.00)

68.00 (20.00)

< 0.001

Male

44.00 (25.00)

44.00 (26.00)

67.00 (16.00)

 

Female

46.00 (26.00)

46.00 (26.00)

68.00 (23.00)

 

Gender (%)

   

0.073

Male

49.19

49.11

57.56

 

Female

50.81

50.89

42.44

 

Race/ethnicity (%)

   

< 0.001

Mexican American

9.07

9.15

1.03

 

Other Hispanic

6.19

6.25

0.60

 

Non-Hispanic White

64.44

64.13

95.44

 

Non-Hispanic Black

11.83

11.94

0.62

 

Other Race

8.47

8.53

2.30

 

Education level (%)

   

< 0.001

Less than high school

16.08

16.19

5.74

 

High school

23.20

23.29

14.81

 

More than high school

60.71

60.52

79.45

 

Marital status (%)

   

0.084

Married/living with partner

63.00

62.94

69.46

 

Others

37.00

37.06

30.54

 

PIR (median (IQR))

2.90 (3.58)

2.89 (3.59)

4.08 (2.86)

< 0.001

Alcohol consumption level (%)

   

0.002

Heavy

20.07

20.16

11.39

 

Moderate

16.29

16.34

11.29

 

Mild

32.87

32.72

47.67

 

Unknow

30.77

30.78

29.65

 

Smoking status (%)

   

< 0.001

Never

56.57

56.67

46.85

 

Former

23.26

23.07

41.36

 

Now

20.17

20.26

11.79

 

Hypertension (%)

   

< 0.001

Yes

34.54

34.28

60.47

 

No

1.50

1.49

2.88

 

Unknow

63.96

64.23

36.64

 

Fasting plasma glucose (mg/dL) (median (IQR))

100.00 (16.00)

100.00 (16.00)

107.00 (20.00)

< 0.001

Unknow

15276.00

15170.00

106.00

 

Triglycerides (%)

   

0.867

high triglycerides (≥ 150 mg/dL) or drug treatment for elevated triglycerides

11.42

11.42

12.27

 

< 150 mg/dL and no drug treatment for elevated triglycerides

35.34

35.36

33.49

 

Unknow

53.23

53.22

54.23

 

HDL-c (%)

   

0.792

< 40 mg/dL in males or < 50 mg/dL in females

30.38

30.37

31.56

 

≥ 40 mg/dL in males or ≥ 50 mg/dL in females

69.62

69.63

68.44

 

Total cholesterol (mg/dL) (median (IQR))

190.00 (54.00)

190.00 (54.00)

183.00 (64.00)

0.269

BMI (kg/m2) (median (IQR))

27.90 (8.40)

27.90 (8.37)

28.20 (8.30)

0.390

Waist circumference (%)

   

0.010

≥ 102 cm in males and ≥ 88 cm in females

55.76

55.64

67.32

 

< 102 cm in males and < 88 cm in females

44.24

44.36

32.68

 

Circadian syndrome (%)

   

< 0.001

No

57.96

58.07

46.39

 

Yes

18.25

18.09

34.18

 

Metabolic syndrome (%)

   

< 0.001

No

47.37

47.56

29.34

 

Yes

20.01

19.78

42.15

 

Number of MetS components (%)

   

< 0.001

0

16.73

16.89

3.41

 

1

23.93

24.07

12.22

 

2

25.37

25.37

25.41

 

3

22.26

22.10

35.18

 

4

11.71

11.57

23.77

 

5

0.00

0.00

0.00

 

TyG (median (IQR))

8.54 (0.86)

8.54 (0.86)

8.87 (0.79)

< 0.001

TyG-WC (median (IQR))

841.20 (242.27)

840.75 (242.60)

913.21 (213.54)

< 0.001

TyG-WHtR (median (IQR))

4.98 (1.40)

4.97 (1.41)

5.37 (1.44)

0.003

TyG-BMI (median (IQR))

239.98 (86.03)

239.90 (86.15)

250.79 (80.87)

0.099

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