Fig. 4 | Scientific Reports

Fig. 4

From: Andrographolide promotes the ex vivo expansion of CD34+ hematopoietic stem cells derived from human umbilical cord blood

Fig. 4

Effect of AP on the expression of characteristic genes related to HSC stemness. Relative gene expressions as fold change at 7 days of culture with AP; (A) HSC-specific markers and functionally important genes (CD34, CD90, CD133, CD117, ALDH1, ALDH2) and (B) HSC-relevant genes and transcriptional factors (BMI1, HOXB4, GATA-2, RUNX1, and CXCR4). Data is represented as mean ± SEM from three independent experiments. *P < 0.05, **P < 0.01 compared with the control.

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