Table 2 Three-level model analysis of individual characteristics and Spatiotemporal effects influencing tuberculosis treatment failure.

From: A multilevel analysis on spatiotemporal and individual-level determinants of tuberculosis treatment failure in China

Variable

Level

\(\:\widehat{\beta\:}\)

SE

RR (95% CI)

P value

Fixed parameter

β0

-7.704

0.433

–

0.000

Age

–

0.310

0.052

1.4 (1.2,1.5)

0.000

Sex (female as ref.)

Male

0.461

0.060

1.6 (1.4,1.8)

0.000

Diagnosis classification (other types* as ref.)

Hematogenous dissemination

2.657

0.524

14.3 (5.1,39.9)

0.000

 

Secondary

2.267

0.390

9.6 (4.5,20.8)

0.000

Etiology (negative as ref.)

Positive

2.063

0.076

7.9 (6.8,9.2)

0.000

Comorbidity (none as ref.)

Pneumoconiosis

0.335

0.535

1.4 (0.5,4.0)

0.532

 

Diabetes/chronic disease

0.300

0.075

1.3 (1.2,1.6)

0.000

Registration classification (new case as ref.)

Initial treatment failure

0.972

0.122

2.6 (2.1,3.4)

0.000

 

Relapse

0.777

0.076

2.2 (1.9,2.5)

0.000

Time delayed in treatment (≤ 30 days as ref.)

> 30 days

0.146

0.057

1.2 (1.0,1.3)

0.011

Random parameters

Area of case management (three-Level) \(\:{{\upsigma\:}}_{\text{v}}^{2}\)

0.045

0.025

–

0.071

 

Treatment year (two-Level)\(\:{{\upsigma\:}}_{\text{u}}^{2}\)

0.042

0.017

–

0.011

 

Case (one-Level)\(\:{{\upsigma\:}}_{{\upepsilon\:}}^{2}\)

1

–

–

–

  1. *other types: including primary pulmonary tuberculosis, tuberculous pleuritis, and extrapulmonary tuberculosis.