Table 4 Descriptive statistics and comparison between groups for histomorphometry of Masson trichrome stained sections (Two- ways ANOVA test).

From: Cell-Free bone regeneration using dental MSCs secretomes from pulp and gingiva in rabbit tibial defects

Parameter

Duration

Group

Mean

Std. Error

2 ways ANOVA

P value

Mature bone area percentage (%)

3 weeks

Non-interventional

6.58 ± 3.18 E

1.30

0.013*

Collagen

14.01 ± 4.06 D

1.66

hDPSCs secretome

28.193 ± 1.179 B

0.481

hGMSCs secretome

26.71 ± 3.92 B

1.60

6 weeks

Non-interventional

19.560 ± 2.118 C,D

0.865

Collagen

23.41 ± 3.10 B,C

1.27

hDPSCs secretome

45.07 ± 3.94 A

1.61

hGMSCs secretome

44.55 ± 3.88 A

1.59

Immature bone area percentage (%)

3 weeks

Non-interventional

24.54 ± 4.07 C,D

1.66

0.000*

Collagen

36.02 ± 3.40 A,B

1.39

hDPSCs secretome

42.48 ± 4.50 A

1.84

hGMSCs secretome

42.28 ± 2.86 A

1.17

6 weeks

Non-interventional

22.24 ± 5.44 D

2.22

Collagen

30.11 ± 2.57 B,C

1.05

hDPSCs secretome

29.43 ± 3.64 B,C,D

1.49

hGMSCs secretome

25.52 ± 5.54 C,D

2.26

Bone marrow spaces area percentage (%)

3 weeks

Non-interventional

70.58 ± 4.91 A

2.00

0.005*

Collagen

51.81 ± 6.53 B

2.67

hDPSCs secretome

47.53 ± 4.28 B,C

1.75

hGMSCs secretome

46.97 ± 7.62 B,C

3.11

6 weeks

Non-interventional

65.15 ± 6.05 A

2.47

Collagen

41.94 ± 7.09 B,C

2.89

hDPSCs secretome

25.43 ± 3.79 D

1.55

hGMSCs secretome

38.45 ± 4.19 C

1.71

  1. Significance level P < 0.05.
  2. *significant means with different superscript letters are significantly different.
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