Fig. 4 | Scientific Reports

Fig. 4

From: A 2D inflammatory co-culture model for investigating synovial fibroblast and macrophage interactions in rheumatoid arthritis

Fig. 4

(A, B) Gene expression levels of inflammatory cytokines TNF–α and IL–1β respectively, in THP-1, M0 and M1 macrophages, analyzed by qRT–PCR; (C, D) Quantification of TNF–α and IL–1β protein expression in resting and stimulated cells using ELISA; (E–G) Gene expression analysis of matrix metalloproteinase MMP2, MMP3, and MMP9 in THP-1, M0 and M1 macrophages; (H) Gene expression of CD44 in THP-1, M0 and M1 macrophage cells. (n = 3; One way ANOVA, *p < 0.05).

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