Fig. 5

(A, B) Representative SEM images of resting and stimulated synovial fibroblast-like cells from rat, respectively; (C–E) CLSM images of showing immunofluorescence staining of fibroblast specific protein (FSP), cadherin–11 (Cad–11) and CD44 of non–stimulated rFLS (Scale bar: 20 μm); (F–H) CLSM images of fibroblast specific protein (FSP), cadherin–11 (Cad–11) and CD44 of stimulated rFLS (Scale bar: 20 μm); (I) Quantification of the aspect ratio of non–stimulated and stimulated rFLS, indicating morphological polarization; (J–L) Quantitative fluorescence intensity analysis of fibroblast specific protein, cadherin-11 and CD44 in non–stimulated and stimulated rFLS (Student’s t–test, *p < 0.05).