Fig. 3
(A) The RIN3 of alteration frequency, containing mutations, amplifications, deep deletions, and multiple modifications was analyzed using TCGA database. (B) The CNVs percentage of RIN3 in each cancer and different colors representing different types of CNVs in the pie chart. (C) Correlations of CNVs with mRNA expression in the bubble pot. (D) Survival difference between CNVs groups of RIN3 in different cancer was analyzed by Cox regression. (E–G) By using the GSCA web tool to draw the Kaplan–Meier picture which represent prognostic significance of RIN3 CNVs in KIRC. (H) Methylation difference in each cancer was investigated by comparing the methylation of normal samples and cancer samples. (I) Correlation between methylation and mRNA expression of RIN3 in the bubble pot. (J) Survival difference between high and low methylation in each cancer was drawn by univariate Cox regression. (K–M) The Kaplan–Meier survival bights were used to describe RIN3 methylation in KIRC.
