Table 1 Antimicrobial activity of the newly synthesized compounds.
Compound No. | MIC (µg/mL) and inhibition zone (mm) | ||
|---|---|---|---|
Gram Positive bacteria | Gram Negative bacteria | Fungi | |
S. aureus | E. coli | C. albicans | |
ATCC: 6538 | ATCC: 9637 | ATCC: 10,231 | |
2 | 100 (14) | 100 (14) | 100 (14) |
4 | 50 (17) | 100 (15) | 100 (14) |
6 | 25 (28) | 25 (29) | 50 (19) |
7 | 50 (18) | 50 (17) | 100 (14) |
8 | 25 (27) | 50 (18) | 100 (14) |
10 | 25 (28) | 50 (17) | 100 (15) |
12 | 25 (27) | 50 (18) | 50 (17) |
13 | 25 (27) | 25 (27) | 50 (19) |
14 | 12.5 (35) | 25 (28) | 50 (18) |
16 | 12.5 (34) | 25 (26) | 50 (17) |
17 | 6.25 (40) | 25 (28) | 12.5 (34) |
18 | 3.125 (44) | 3.125 (43) | 6.25 (39) |
19 | 3.125 (44) | 3.125 (44) | 6.25 (40) |
20 | 12.5 (36) | 25 (27) | 25 (25) |
21 | 6.25 (40) | 25 (27) | 50 (17) |
22 | 6.25 (39) | 25 (28) | 12.5 (35) |
23 | 3.125 (43) | 3.125 (44) | 6.25 (40) |
24 | 50 (17) | 50 (17) | 100 (15) |
25 | 50 (17) | 50 (16) | 100 (14) |
Chloramphenicol | 3.125 (44) | 6.25 (37) | NT |
Cephalothin | 6.25 (36) | 6.25 (38) | NT |
Cycloheximide | NT | NT | 3.125 (42) |
