Table 3 The selectivity index (SI) and IC50 of MOF and SOR before and after loading on HFb-4, HepG2, and HCT-116 cell lines.

From: MOF enhances the sensitivity and selectivity of sorafenib as an anticancer drug against hepatocellular carcinoma and colorectal cancer in vitro

Cell line

IC50 SOR

SI

IC50 SOR-MIL-53

before correction

IC50 SOR-MIL-53

after correction

SI

HFb-4

5.88 µg/ml

-

14.22 µg/ml

3.3 µg/ml

-

HepG2

12.58 µg/ml

0.46

23.49 µg/ml

5.5 µg/ml

0.6

HCT-116

12.73 µg/ml

0.2

33.72 µg/ml

7.9 µg/ml

0.42

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