Table 3 Comparison of obstetric and neonatal outcomes between no-drugs, 1 or 2 drugs, and ≥ 3 psychotropic drugs groups.
Total N = 358 | No drug N = 177 | 1 or 2 drugs N = 139 | ≥ 3 drugs N = 42 | P-value | |||
|---|---|---|---|---|---|---|---|
No drug vs 1 or 2 | 1 or 2 vs ≥ 3 | No drug vs ≥ 3 | |||||
Gestational ages at delivery | 38 (37–41) | 38 (37–41) | 38 (37–41) | 38 (37–40) | 0.68 | 0.31 | 0.20 |
HDP | 24 (6.7%) | 10 (5.6%) | 10 (7.2%) | 4 (9.5%) | 0.58 | 0.62 | 0.36 |
GDM | 40 (11%) | 20 (11%) | 14 (10%) | 6 (14%) | 0.73 | 0.45 | 0.59 |
Epidural anesthesia | 205 (37%) | 95 (54%) | 85 (61%) | 25 (59%) | 0.18 | 0.85 | 0.49 |
Cesarean section | 105 (29%) | 58 (33%) | 31 (22%) | 16 (38%) | 0.14 | 0.14 | 0.74 |
Blood loss(g) | 751 (145–3353) | 784 (145–2616) | 723 (250–3353) | 779 (270–1994) | 0.47 | 0.79 | 0.84 |
Birth Weight(g) | 2963 (1850–4102) | 2966 (1850–3738) | 2952 (1950–3878) | 2990 (2154–4102) | 0.64 | 0.45 | 0.52 |
LFD | 38 (11%) | 17 (9.6%) | 13 (9.4%) | 8 (19%) | 0.94 | 0.08 | 0.08 |
SGA | 30 (8.4%) | 18 (10%) | 8 (5.8%) | 4 (9.5%) | 0.16 | 0.39 | 0.90 |
Apgar score at 1 min | 8 (0–10) | 8 (0–9) | 8 (1–9) | 8 (1–10) | 0.04 | 0.50 | 0.056 |
Apgar score at 5 min | 9 (1–10) | 9 (3–10) | 9 (1–10) | 9 (4–10) | 0.33 | 0.19 | 0.032 |
Umbilical artery pH | 7.31 (6.93–7.48) | 7.31 (6.95–7.48) | 7.29 (6.93–7.48) | 7.31 (7.15–7.39) | 0.39 | 0.43 | 0.74 |
NICU admission | 51 (14%) | 25 (14%) | 14 (10%) | 12 (29%) | 0.28 | 0.0028* | 0.025 |
Respiratory ventilator treatment | 15 (4.2%) | 4 (2.3%) | 6 (4.3%) | 5 (12%) | 0.30 | 0.07 | 0.0047* |
NAS | 9 (2.5%) | 0 (0%) | 4 (2.9%) | 5 (12%) | 0.023 | 0.0189 | < 0.0001* |
Congenital Anomalies | 18 (5.0.%) | 10 (5.6%) | 6 (4.3%) | 2 (4.8%) | 0.59 | 0.91 | 0.82 |
