Table 3 Brain injury on conventional MRI according to the severity of hypoxic ischemic encephalopathy.

From: ASL reveals regional brain perfusion impairment in neonates with mild hypoxic ischemic encephalopathy

Areaa

Grade

Mild HIE

(N = 74)

Moderate HIE (N = 15)

Severe HIE (N = 5)

P valueb

Basal ganglia and thalami

0

72 (97.3)

11 (73.3)

1 (20)

< 0.001

1

1 (1.3)

1 (6.7)

4 (80)

2

1 (1.3)

3 (20)

0

PLIC

0

74 (100)

14 (93.3)

0

< 0.001

1

0

1 (6.7)

0

2

0

0

2 (40)

3

0

0

3 (60)

White Matter

0

45 (61)

10 (66.7)

0

0.006

1

13 (17.6)

2 (13.3)

4 (80)

2

16 (22)

3 (20)

1 (20)

Cortex

0

66 (89.2)

13 (86.6)

1 (20)

< 0.001

1

7 (9.5)

1 (6.7)

3 (60)

2

1 (1.3)

1 (6.7)

1 (20)

  1. MRI, Magnetic resonance imaging, HIE, Hypoxic ischemic encephalopathy.
  2. a Data are presented as a number (percentage); b P values for the differences of ordinal variables between the three groups was determined by linear-by-linear association.