Fig. 1 | Scientific Reports

Fig. 1

From: Astaxanthin mitigates cardiac toxicity induced via doxorubicin by alleviating mitochondrial fission and autophagy in rats

Fig. 1

ASTA can increase the left ventricular ejection fraction and left ventricular fractional shortening induced by DOX. (A) Representative M-ultrasound images in each group. (B) The results of EF in each group. Dox decreased the EF in rats, and ASTA treatment resulted in a statistically significant increase in EF compared to the DOX group. (C) The result of FS in each group. Dox decreased the FS in rats, and ASTA treatment resulted in a statistically significant increase in FS compared to the DOX group. Values are expressed as the mean ± standard deviation. Sham group: n = 3; other groups: n = 6 each. *P < 0.05. ns: no significance. DOX: Doxorubicin; ASTA: Astaxanthin; EF: Ejection fraction; FS: Fractional shortening.

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