Table 3 Relationships between clinical characteristics and ALP and LDH levels in MBC patients.

From: Evaluation of serum alkaline phosphatase and lactate dehydrogenase as predictive biomarkers for the prognosis of male breast cancer

Variables

number

ALP

LDH

low

high

P value

low

high

P value

Age at diagnosis, y

   

0.679

  

0.489

<66

39

33

6

 

31

8

 

≥ 66

41

36

5

 

35

6

 

BMI

      

0.643

<24

47

40

7

 

38

9

 

≥ 24

33

29

4

 

28

5

 

Clinical staging

   

0.216

  

0.302

I

17

16

1

 

15

2

 

II

37

33

4

 

32

5

 

III

26

20

6

 

19

7

 

T stage

   

0.312

  

0.777

T1

25

21

4

 

22

3

 

T2

34

30

4

 

27

7

 

T3

13

10

3

 

11

2

 

T4

8

8

0

 

6

2

 

N stage

   

0.671

  

0.173

N0

45

40

5

 

40

5

 

N1

20

16

4

 

15

5

 

N2

11

10

1

 

9

2

 

N3

4

3

1

 

2

2

 

Molecular typing

   

0.721

  

0.551

Luminal A

63

53

10

 

52

11

 

Luminal B

12

11

1

 

10

2

 

HER-2 overexpression

2

2

0

 

1

1

 

Triple negative

3

3

0

 

3

0

 
  1. ALP, alkaline phosphatase; LDH, lactate dehydrogenase; BMI, body mass index; HER-2, human epidermal growth factor receptor 2.