Fig. 2 | Scientific Reports

Fig. 2

From: Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats

Fig. 2

Open field activity of prepubertal rats exposed to nandrolone. Prepubertal males were injected daily with nandrolone (20 mg/kg) or sesame oil from PN 28–37. On days 39 and 40, rats were tested for open-field behavior (see Fig. 1A). Rats were placed in the activity cage, and the time spent in the center of the field, as well as the distance traveled, was recorded for 10 min using the Accuscan Versamax monitoring system. Rats treated with nandrolone (20 mg/kg) spent more time in the center of the open field (A) and traveled less distance on days 0 (B) and 1 (C) than oil-treated rats. Data are presented as mean ± SEM (n = 10) and were analyzed with a Student’s t-test. Asterisks represent a significant difference compared to the oil group.

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