Fig. 3 | Scientific Reports

Fig. 3

From: Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats

Fig. 3

Results from the EPM test of prepubertal rats treated with nandrolone. Male rats were injected daily with nandrolone (20 mg/kg) or sesame oil from PN 28–37 and tested in the elevated plus maze on day 38. Rats were placed at the junction between the open and closed arms, and behavioral activity was recorded for 5 min using the ANY-MazeÔ tracking software. Rats treated with nandrolone spent more time in the open arms (A), an indication of decreased anxiety. In addition, rats that received nandrolone had fewer total entries than oil-treated rats (B), an indication of reduced ambulation. Data are presented as mean ± SEM (n = 10) and analyzed with a Student t-test. Asterisks represent a significant difference compared to oil-treated rats.

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