Table 6 Comparison of serum vitamin levels between the preoperative and 1-month postoperative period in subgroup analysis.

From: The strategy of vitamin supplementation in Chinese patients with gastric cancer after gastrectomy: a prospective cohort study

Subgroup

Project

Time

Control group

Experimental group

P-valuea

Total gastrectomy

(N = 40)

Folic acid (ng/mL)

Preoperative

4.33(3.17–4.74)

4.61 (3.73–8.23)

0.194

1-month postoperative

4.88 (4.08–5.84)*

4.54 (3.91–7.27)

0.735

Difference value

1.28 ± 2.81

0.57 ± 3.37

0.472

Vitamin B12 (pg/mL)

Preoperative

264.30 (219.27-321.47)

243.29 (210.65-294.37)

0.675

1-month postoperative

295.98 (269.71–330.10)

302.72 (272.12-390.66)*

0.198

Difference value

14.09 ± 102.76

82.06 ± 112.86

0.053

25-hydroxyvitamin D (ng/mL)

Preoperative

9.06 (8.31–9.51)

8.91 (7.85–9.77)

0.665

1-month postoperative

8.29 (7.74–9.44)

8.79 (7.45–11.45)

0.440

Difference value

-0.46 (-1.42-0.66)

-0.07 (-1.00-1.49)

0.542

Vitamin B1 (nmol/L)

Preoperative

57.92 ± 2.72

52.57 ± 1.35

0.059

1-month postoperative

55.18 (49.79–59.68)

57.00 (51.59–65.12)*

0.453

Difference value

-1.57 (-3.88-5.04)

7.27 (-2.22-11.73)

0.078

Partial gastrectomy

(N = 38)

Folic acid (ng/mL)

Preoperative

4.42 (3.90–6.10)

5.34 (3.96–6.63)

0.378

1-month postoperative

4.76 (4.01–6.50)

6.36 (4.63–9.88)

0.106

Difference value

-0.30 (-1.10-2.14)

0.88 (-0.12-3.34)

0.182

Vitamin B12 (pg/mL)

Preoperative

318.60 ± 78.68

320.81 ± 79.37

0.932

1-month postoperative

292.55 (248.59-422.12)

344.28 (233.96-427.71)

0.692

Difference value

14.08 (-91.36-111.31)

4.79 (-25.73-111.44)

0.670

25-hydroxyvitamin D (ng/mL)

Preoperative

8.64 (7.98–9.28)

9.03 (8.25–9.45)

0.394

1-month postoperative

9.02 (7.98–9.88)

9.54 (8.74–10.43)

0.258

Difference value

0.15 (-0.35-1.08)

0.58 (-0.58-1.27)

0.500

Vitamin B1 (nmol/L)

Preoperative

49.94 (46.51–54.05)

55.43 (49.79–59.53)

0.126

1-month postoperative

54.83 (50.74–64.62)

66.80 (58.30–81.50)*

0.013†

Difference value

5.73 ± 2.78

19.63 ± 5.93

0.045†

  1. *P-value < 0.05 versus preoperative serum vitamin levels within the experimental group or the control group. aCalculated by parametric (t-test) or nonparametric (Wilcoxon) as appropriate. †P-value < 0.05.
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