Table 1 Comparison of baseline measurements between the two groups.

From: A randomized trial on the feasibility of high-intensity interval training during chemotherapy in young breast cancer patients

Parameter [unit]

CTR (pre-training)

HIIT (pre-training)

p-value

Mean/median

Mean/median

n = 21

n = 19

Age [years]

34.9

34.4

0.6812

 95% CI

(33.0 — 36.8)

(32.4 — 36.3)

 

Weight [kg]

65.8

68.1

0.6261

 95% CI

(58.3 — 73.3)

(62.2 — 74.1)

 

BMI [kg/m2]‡

22.4

23.1

0.8513

 95% CI

(19.3 — 27.0)

(19.9 — 26.3)

 

Muscle mass [kg]

44.5

45.5

0.5329

 95% CI

(40.2 — 49.2)

(43.1 — 48.3)

 

Fat mass [kg]

14.7

19.5

0.4364

 95% CI

(10.8 — 23.9)

(12.8 — 24.8)

 

Grip strength [kg]

 Affected side

29.1

32.1

0.0630

  95% CI

(27.1 — 31.2)

(29.6 — 34.6)

 

 Unaffected side

30.5

33.1

0.0621

  95% CI

(24.5 — 33.5)

(29.1 — 38.0)

 
 

n(%)

n(%)

 

Tumour profile

 T1

3(15.79)

3(14.29)

> 0.9999

 T2

10(52.63)

12(57.14)

 T3

6(31.58)

5(23.81)

 T4

0(0)

1(4.76)

 N0

11(57.89)

14(66.67)

0.5801

 N+

6(31.58)

6(28.57)

 N2

2(10.53)

1(4.76)

Therapy

 Doxorubicin

21(100)

19(100)

N/A

 Paclitaxel

15(78.95)

16(76.19)

0.5568

 Carboplatin

6(31.58)

5(23.81)

0.8454

 Trastuzumab

8(42.11)

11(52.38)

0.3497

 Docetaxel

3(15.79)

2(9.52)

0.9047

 Pertuzumab

2(10.53)

3(14.29)

0.9047

 Epirubicin

0(0.00)

1(4.76)

0.9596

 Cyclophosphamide

0(0.00)

1(4.76)

0.9596

  1. The values are means with 95% confidence intervals or medians with interquartile ranges.
  2. CI = confidence interval; CTR = control; HIIT = high-intensity interval training; - median; - (first quartile—third quartile); Student’s t-test (for normal distribution), Mann-Whitney U test (for nonnormal distribution and for frequency comparisons of tumour profile data), or chi-square test (for frequency comparisons of therapy data) were used for between-group comparisons; the tumour profile was based on TNM classification27; the results were rounded to the first decimal place.