Table 3 Serum levels of biochemical indicators in the different study groups. No significant changes were observed in any of the indicators in any of the groups. (ALT: Alanine aminotransferase, AST: aspartate aminotransferase, ALP: alkaline phosphatase, BUN: blood Urea Nitrogen).

From: Nanoliposome loaded with 5-fluorouracil and Dorema aucheri extract reduces tumor growth in a mouse model of colorectal cancer

 

ALT

(U/L)

AST

(U/L)

ALP

(U/L)

Total Bilirubin

(mg/dl)

Albumin

(g/dl)

BUN

(mg/dl)

Creatinine

(mg/dl)

Contorol

36 ± 8.3

49 ± 6.8

125 ± 5.7

0.4 ± 0.1

3.3 ± 1.1

11.2 ± 4.9

0.3 ± 0.1

NLP

37 ± 7.1

52 ± 7.9

122 ± 8.9

0.5 ± 0.2

3.9 ± 1.4

13.4 ± 3.2

0.4 ± 0.2

DA

38 ± 5.9

44 ± 6.4

134 ± 5.8

0.5 ± 0.2

4.1 ± 1.2

12.2 ± 3.1

0.3 ± 0.2

5FU

40 ± 6.6

58 ± 8.6

140 ± 4.7

0.6 ± 0.2

3.7 ± 2

11.1 ± 4.5

0.5 ± 0.2

NLP + DA

39 ± 7.4

60 ± 5.8

136 ± 6.3

0.4 ± 0.1

3.4 ± 1.8

10.9 ± 5.8

0.4 ± 0.1

NLP + 5FU

41 ± 6.2

59 ± 6.9

137 ± 7.9

0.5 ± 0.2

4.2 ± 1.8

11.4 ± 5.2

0.4 ± 0.2

DA + 5FU

43 ± 5.1

54 ± 4.9

141 ± 5.6

0.6 ± 0.1

4.9 ± 1.1

15 ± 2.9

0.5 ± 0.1

NLP + 5FU + DA

42 ± 4.9

54 ± 6.4

137 ± 7.1

0.5 ± 0.1

4.5 ± 1.2

14.8 ± 3.4

0.5 ± 0.2