Fig. 3
From: Whole organism integrated DNA methylation and transcriptomics analysis of butterfly metamorphosis
Genes exhibiting significant differential isoform use are enriched for functions associated with ATP biosynthesis, glycolysis and carbohydrate metabolism. (a) Significant functional categories identified in the differential expression results for P2 v P0, P4 v P0, and P6 v P0. In each panel, the y-axis corresponds to –log10(padj) such that more significant categories are displayed at higher values, and the x-axis indicates the number of genes in the input list that generate the significant result. The horizontal lines mark a padj = 0.05 threshold. All the significant categories are from the GO BP ontology. All significant functional enrichment results for all the clusters in panel are provided in data S5. The plots were generated from these results after excluding redundant categories related to purine nucleoside biosynthesis. (b) Genes exhibiting significant differential splicing between stage P0 and the later developmental stages from the enriched functional categories ATP biosynthesis, glycolysis, and carbohydrate metabolism. Panels are as described in the legend to Fig. 1.
