Fig. 2
From: S-ketamine relieves neuropathic pain by inhibiting microglia phagocytosis of the perineuronal nets
CCI-induced neuroinflammation and microglial reaction. (A) Representative WB pictures of inflammatory factors at preoperative and postoperative days 3, 7, 14, 21, and 28 (N = 6). (B) Quantification of inflammatory factors IL-1β and IL-6 (N = 6). (C) Representative fluorescence images of spinal dorsal horn IBA1(microglia marker) (N = 6). (D) Number of IBA1 positive cells (N = 6). *P < 0.05, **P < 0.01 and ***P < 0.001 compared with D0 (day 0); One-way ANOVA with Bonferroni post-hoc testing was conducted.
