Fig. 1

Representative case of soft drusen (SD) alone (A–D) and both SD and subretinal drusenoid deposit (SDD) (E–H). SDD includes both dot and ribbon type SDD. (A) and (E) are fundus photos. (B) and (F) are blue peak fundus autofluorescence (FAF) images. (C) and (G) are infrared reflectance images (IR). (D) and (H) shows pointwise retinal sensitivity and optical coherence tomography (OCT). FAF, IR, and OCT were acquired using the Spectralis OCT device. All images are aligned to display the same retinal region. The MAIA-derived pointwise retinal sensitivity is superimposed on the FAF image. The OCT B scan corresponds to the green arrow in the IR image. Areas outlined in blue indicate SD, while areas within green lines correspond to dot-type SDD. Note that retinal sensitivity is reduced in the area with SDD (H) compared to the region with SD alone (D).