Fig. 1
From: Artifact detection in fluorescence microscopy using convolutional autoencoder
(A) Schematic representation of sFIDA technology. The capture antibody is immobilized on the glass surface. Both oligomers and monomers can bind to the capture antibodies. However, only oligomers can be detected by fluorescence signalling, as the epitope of the monomers is masked by the capture antibody, preventing fluorescently labeled detection antibodies from binding. Created with BioRender.com. (B) Example of sFIDA-generated image, showing signals from Aβ-coated SiNaPs. The image was colorized and contrast has been increased to enhance visibility. The scalebar is equal to 10 μm.
