Table 4 Univariate and multivariate analysis of ordered logistic regression.

From: Modified RECIST submodels and ordinal regression model predict neoadjuvant chemoimmunotherapy response in locally advanced gastric cancer​​

Univariate

Multivariate

Influence Factor

β (95% CI)

P

Value

OR (95% CI)

β (95% CI)

P

Value

OR (95% CI)

CPS

0.043

(−0.02, 0.106)

0.181

1.044

(0.980,1.112)

   

SⅡ

0.000

(−0.001,0.001)

0.707

1.000

(0.999, 1.001)

   

PNI

−0.008

(−0.033,0.018)

0.553

0.992

(0.968,1.018)

   

PLR

−0.001

(−0.006,0.004)

0.653

0.999

(0.994,1.004)

   

NLR

−0.158

(−0.568,0.252)

0.450

0.854

(0.567,1.287)

   

Differentiation

0.577

(−0.101, 1.256)

0.095

1.781

(0.904,3.512)

   

USBWR rate

−7.189

(−10.706, 3.672)

< 0.001*

0.001 (< 0.001,0.025)

−8.025

(−12.939, 3.110)

0.001*

0.0003

(< 0.001, 0.045)

CT-LNSAR rate

−10.394

(−14.577, −6.211)

< 0.001*

< 0.001 (< 0.001,0.002)

−9.605

(−14.280, 4.931)

< 0.001*

0.0001

(< 0.001, 0.007)

CT-TTR rate

−7.743

(−11.247, −4.238)

< 0.001*

< 0.001(< 0.001, 0.014)

−4.574

(−8.559, −0.589)

0.024*

0.0103

(0.0002, 0.555)

  1. Statistical Details: Test Method: Ordinal logistic regression, Justification: Appropriate for ordinal outcome variables with continuous/categorical predictors,αLevel:0.05 (two-sided); Proportional Odds Assumption: Met (Brant test, p = 0.32);Sample Size: Total n = 75 (TRG 0–1: 37,TRG2: 26, TRG3: 12);Reference Category: Highest ordered category (TRG3);P Value Notation: * indicates statistical significance (p < 0.05).
  2. OR: Odds Ratio. CI: Confidence Interval. CPS: Combined Positive Score.SⅡ: Systemic Immune-Inflammation Index. PNI: Prognostic Nutritional Index. PLR: Platelet-to-Lymphocyte Ratio. NLR: Neutrophil-to-Lymphocyte Ratio. CI: Confidence Interval. USBWR: Ultrasonography-based Basal Width Reduction Rate. CT-LNSAR: CT-based lymph node short-axis reduction rate. CT-TTR: CT-based tumor thickness reduction rate.
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