Table 2 Distribution pattern of TAMs in ccRCC.
From: CD68- and CD163-positive tumor-associated macrophages in renal clear cell carcinoma
Clinicopathological features | CD68 | CD163 | CD163/CD68 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumor nest | Tumor stroma | Tumor nest | Tumor stroma | Tumor nest | Tumor stroma | ||||||||||||||||
Low | High | P value | Low | High | P value | Low | High | P value | Low | High | P value | Low | High | P value | Low | High | P value | ||||
Age (years) | < 0.001 | < 0.001 | 0.031 | 0.310 | 0.011 | 0.121 | |||||||||||||||
≤ 63 | 23 | 31 | 18 | 36 | 24 | 30 | 25 | 29 | 21 | 33 | 23 | 31 | |||||||||
> 63 | 42 | 10 | 45 | 7 | 34 | 18 | 19 | 33 | 33 | 19 | 30 | 22 | |||||||||
Gender | 0.821 | 0.239 | 0.349 | 0.368 | 0.084 | 0.449 | |||||||||||||||
Male | 43 | 28 | 36 | 35 | 42 | 29 | 36 | 35 | 34 | 37 | 35 | 36 | |||||||||
Female | 22 | 13 | 22 | 13 | 24 | 11 | 21 | 14 | 23 | 12 | 20 | 15 | |||||||||
Tumor size (cm) | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.012 | 0.501 | |||||||||||||||
≤ 5 | 53 | 4 | 46 | 11 | 55 | 2 | 47 | 10 | 36 | 21 | 30 | 27 | |||||||||
> 5 | 12 | 37 | 12 | 37 | 9 | 40 | 10 | 39 | 19 | 30 | 29 | 20 | |||||||||
Histological grade | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.195 | 0.320 | |||||||||||||||
Ⅰ-Ⅱ | 54 | 24 | 52 | 26 | 53 | 25 | 54 | 24 | 39 | 39 | 42 | 36 | |||||||||
Ⅲ-Ⅳ | 11 | 17 | 1 | 27 | 2 | 26 | 1 | 27 | 10 | 18 | 12 | 16 | |||||||||
Lymph node metastasis | 0.001 | 0.034 | 0.009 | 0.006 | 0.132 | 0.642 | |||||||||||||||
No | 64 | 33 | 57 | 40 | 64 | 33 | 57 | 40 | 50 | 47 | 51 | 46 | |||||||||
Yes | 1 | 8 | 2 | 7 | 2 | 7 | 1 | 8 | 7 | 2 | 4 | 5 | |||||||||
Mortality | 0.054 | 0.135 | 0.003 | 0.014 | 0.166 | 0.166 | |||||||||||||||
No | 63 | 36 | 57 | 42 | 69 | 30 | 61 | 38 | 55 | 44 | 55 | 44 | |||||||||
Yes | 2 | 5 | 2 | 5 | 1 | 6 | 1 | 6 | 2 | 5 | 2 | 5 | |||||||||
