Table 3 Univariate and multivariate Cox regression analyses for overall survival (OS) in patients with ccRCC.
From: CD68- and CD163-positive tumor-associated macrophages in renal clear cell carcinoma
Clinicopathological features | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OS HR (95% CI) | P value | OS HR (95% CI) | P value | |
Age (≤ 63 vs. > 63) | 3.66 (0.38–5.28) | 0.260 | ||
Gender (Male vs. Female) | 1.05 (0. 61–7.91) | 0.965 | ||
Tumor size (≤ 5 cm vs. > 5 cm) | 3.99 (0.41–8.39) | 0.231 | ||
Histological grade (Ⅰ-Ⅱ vs. Ⅲ-Ⅳ) | 2.89 (0.32–4.30) | 0.990 | ||
Lymph node metastasis (No vs. Yes) | 4.62 (1. 41–7.27) | 0.982 | ||
TN CD68 (low vs. high) | 3.21 (0.11–21.64) | 0.416 | ||
TS CD68 (low vs. high) | 4.33 (0.33–65.47) | 0.752 | ||
TN CD163 (low vs. high) | 7.57 (1.83–28.80) | 0.035 | 7.21 (1.05–25.54) | 0.037 |
TS CD163 (low vs. high) | 3.78 (1.13–16.47) | 0.041 | 3.55 (1.03–15.55) | 0.045 |
TN CD163/CD68 (low vs. high) | 3.02 (0.11–13.33) | 0.135 | ||
TS CD163/CD68 (low vs. high) | 0.99 (0.10–3.38) | 0.755 | ||
