Fig. 1
From: Nasopharyngeal and oral microbiota profiling in SARS-CoV-2 infected pregnant women
(A) Stacked bar plots showing the relative abundance of the 10 most prevalent genera in the nasopharyngeal and oral microbiota of non-infected (healthy), asymptomatic (SCoV-2_A), and symptomatic (SCoV-2_S) SARS-CoV-2 infected pregnant women. Each bar represents an individual sample, with genera ordered by their relative abundance across all samples. (B–D) Alpha- and beta-diversity analyses measured using the Shannon index, and unweighted, weighted and Bray-Curtis distance matrices in nasopharyngeal (N) vs. oral (O) swabs in (B) non-infected (healthy) pregnant women, (C) asymptomatic (SCoV-2_A) SARS-CoV-2 infected pregnant women and (D) symptomatic (SCoV-2_S) SARS-CoV-2 infected pregnant women. Alpha-diversity was evaluated using the Shannon index. Comparisons of alpha-diversity between nasopharyngeal and oral microbiota were performed using the Wilcoxon rank-sum test (Healthy, P = 0.11; SCoV-2_A, P = 0.091; SCoV-2_S, P = 0.29). Beta-diversity analysis between nasopharyngeal and oral microbiota was conducted using PERMANOVA, for the Unweighted UniFrac distance (Healthy, P = 0.001; SCoV-2_A, P = 0.001; SCoV-2_S, P = 0.003), the Weighted UniFrac distance (Healthy, P = 0.001; SCoV-2_A, P = 0.001; SCoV-2_S, P = 0.001), and the Bray-Curtis dissimilarity index (Healthy, P = 0.001, SCoV-2_A, P = 0.001; SCoV-2_S, P = 0.001).
