Table 4 Comparison of outcomes of BL/BLI administration between propensity score-matched ABPC/SBT and PIPC/TAZ cohorts.

From: Ampicillin sulbactam impacts serum potassium level comparable to piperacillin tazobactam

 

Propensity score-matched

 

ABPC/SBT cohort (n = 59)

PIPC/TAZ cohort (n = 59)

Result of analysis

Change in SPL (mEq/L)

 − 0.28 ± 0.47

 − 0.35 ± 0.51

P = 0.443

Percent decrease in SPL (%)

10.7 ± 7.0

11.0 ± 9.7

P = 0.822

Incidence of hypokalemia during BL/BLI administration (%)

25.4

27.1

P = 1.000,

OR = 1.091,

95%CI = 0.443–2.696

Incidence of hypokalemia

within 3 days after starting administration (%)

3.4

8.5

P = 0.439,

OR = 0.382,

95%CI = 0.035–2.453

Incidence of hypokalemia

within 5 days after starting administration (%)

18.6

16.9

P = 1.000

OR = 1.122,

95%CI = 0.392–3.249

Incidence of hypokalemia

within 7 days after starting administration (%)

20.3

18.6

P = 1.000,

OR = 1.113,

95%CI = 0.405–3.090

Incidence of hypokalemia

within 14 days after starting administration (%)

23.7

23.7

P = 1.000,

OR = 1.000,

95%CI = 0.392–2.554

  1. BL/BLI, beta-lactam/beta-lactamase inhibitor combination; ABPC/SBT, ampicillin/sulbactam; PIPC/TAZ, piperacillin/tazobactam; SPL, serum potassium level; OR, odds ratio; 95%CI, 95% confidence interval.