Table 1 Mean ± SEM values for pregnancy and embryo metrics.

From: Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor

Pregnancy Metrics

Exposure

One-Way ANOVA effect of aerosol exposure

Mixed Model ANOVA

Room air

E-liquid

E-cigarette

F(DF)

p value summary

Effect

F

p value summary

Maternal body weight at the start of acclimation

30.7 ± 1.54

32.85 ± 1.54

32.0 ± 1.54

0.49(2)

n.s

   

Maternal body weight at conception (GD0)

29.42 ± 1.52

31.0 ± 1.52

32.35 ± 1.52

1.08(2)

n.s

   

Percent change in Maternal body weight†

GD10

GD13

GD15

14.06 ± 4.15

26.78 ± 5.35

44.22 ± 7.25

13.25 ± 4.31

27.21 ± 8.63

39.99 ± 12.25

10.92 ± 3.17

26.94 ± 3.74

44.57 ± 5.49

 

Aerosol exposure

Gestational day

Aerosol exposure x gestational day

0.16(2,27)

62.24(2,27)

0.34(4,27)

n.s

****

n.s

 

Embryo metrics

Embryos per pregnancy on E15

10.50 ± 1.01

9.75 ± 1.01

10.50 ± 1.01

0.18(2,9)

n.s

   

Embryo crown to rump length on E15 (mm)

13.97 ± 0.12

13.96 ± 0.12

113.97 ± 0.12

0.92(2,9)

n.s

   
  1. † percentage of baseline bodyweight on gestational day 0 (GD0). E = embryonic day; One-way and Mixed Model ANVOAs.
  2. **** p < 0.0001; n.s. = not significant.