Fig. 3
Antigenic cartography. (a) An antigenic map from convalescent data up to 1 month post first available data was constructed. Variants are shown as labeled, colored circles and sera are shown as open squares with the color matching the infecting variant. The x- and y-axes correspond to relative antigenic distances, each grid line reflects an additional 2-fold dilution in the neutralization assay. (b) An antigenic map constructed from all convalescent data with arrows pointing to the variants’ positions in a. (c) Comparison of the map by Wilks et al.19. to the full data map in b and (d) the map by Roessler et al.22. to the full data map in b. Arrows point to the variants’ positions in the respective map. The numbers on the bottom left corner show the stress of the map. (e-f) GMT antibody landscapes for the 2x Vax (grey), 3x Vax (dark grey) and Vax + BA.1 (red) serum groups are shown, subset to early data up to 1 month post first report (e), medium data up to 90 days post first report (f) and all data (g). GMTs against variants are indicated by impulses.
