Fig. 5
From: Ptbp1 knockdown induces conversion of rat spinal cord astrocytes into neuron like cells
LPS and DEX resulted in different inflammatory states of astrocytes. (A) Comparison of GFAP mRNA levels between non-reactive astrocytes and LPS-induced reactive astrocytes, with results normalized to the non-reactive astrocytes group (two-tailed Student’s t-test). (B) Comparison of C3 mRNA levels between non-reactive astrocytes (Lucid), LPS-induced reactive astrocytes (LPS), and DEX-reversed reactive astrocytes (LPS + DEX), with results normalized to the Lucid group (one-way ANOVA followed by Bonferroni post hoc test). (C) Comparison of CCL2 mRNA levels between Lucid, LPS, and LPS + DEX groups, with results normalized to the Lucid group (one-way ANOVA followed by Bonferroni post hoc test). (D) Comparison of IL-10 mRNA levels between Lucid, LPS, and LPS + DEX groups, with results normalized to the Lucid group (one-way ANOVA followed by Bonferroni post hoc test). All data are presented as means ± SD. The experiments were performed three times. **P < 0. 01 and ***P < 0.001. LPS: lipopolysaccharide; DEX: dexamethasone; ns: no significance.
