Table 4 Stability studies of the optimized nanomatrices (PCD-6).
Sr. No. | Parameters | 0 month | 3rd month | 6th month |
|---|---|---|---|---|
1. | Physical appearance | Initially white in color | Nanomatrices were white in color | White color nanomatrices were observed |
2. | FTIR spectral arrangement | Performed | Specific spectra were observed at specific wave number | No change or shifting of the peaks was observed. All the specific spectra were present at their specific wave number |
3. | Particle size | Performed | Particle size was found to be constant. Zeta potential and PDI were also the same as observed in initial stage of the stability study | No noticeable change was observed in the particle size. Zeta potential and PDI were also found to be same as that of the original values observed at start of the stability studies |
4. | Percent drug loading | 88.643% | 88.513% | 88.411% |
5. | Swelling ability | Remained constant | No noticeable change was observed in the swelling behavior | No visible change was found |