Fig. 6 | Scientific Reports

Fig. 6

From: Surface electrical impedance myography detects disease in an adult-onset SOD1-G93A zebrafish model of amyotrophic lateral sclerosis

Fig. 6

EIM exhibits good test–retest reliability in both healthy and ALS zebrafish. Analysis of the repeatability of EIM was assessed at 2 kHz by calculating the intra-class correlation coefficient (ICC). In healthy animals (n = 20), test–retest plots at 2 kHz: (A) phase angle, (B) reactance, and (C) resistance. In ALS animals (n = 20), test–retest plots at 2 kHz: (D) phase angle, (E) reactance, and (F) resistance. In healthy and ALS animals (n = 20), Bland–Altman plots of EIM parameters for 2 kHz (G,H) phase angle, (I,J) reactance, and (K,L) resistance. Red lines = the Bland–Altman 95% limits of agreement; purple line = the estimated mean difference; dotted line = the reference line of perfect average agreement (y = 0).

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