Fig. 4
From: Comparative evaluation of amiodarone and furosemide compatibility under different mixing conditions

pH changes in mixtures containing varying amiodarone and furosemide doses The graphs illustrate the pH changes in the mixtures prepared using SM and RM containing different amiodarone and furosemide doses, along with the pH differences between the two methods. Amiodarone was infused at 25.5 mg/h (corresponding injection volume: SM 1.7 mL, RM 17 mL/h). Furosemide was infused at 5 mg/h (SM 50 µL, RM 0.5 mL/h), 8 mg/h (SM 80 µL, RM 0.8 mL/h), or 10 mg/h (SM 100 µL, RM 1.0 mL/h). Data are presented as the mean ± standard deviation of three samples. N.S. not significant, *p< 0.05, **p < 0.01, #p < 0.001 SM 5 mg/h vs. SM 10 mg/h, ##p < 0.001 SM 8 mg/h vs. SM 10 mg/h, ▲p< 0.001 RM 5 mg/h vs. RM 10 mg/h, ■p < 0.05 RM 5 mg/h vs. RM 8 mg/h: Tukey’s multiple comparison test.