Fig. 4 | Scientific Reports

Fig. 4

From: Comprehensive analysis of microRNA expression provides mechanistic insights into transcriptomic alteration in primary and metastatic testicular germ cell tumors

Fig. 4The alternative text for this image may have been generated using AI.

Enrichment analysis of inferred target genes reveals diverse biological processes and related complex traits targeted by marker miRNAs in each subtype. Shown are −log p-value of enrichment of five classes biological processes (WikiPathways, Reactome, IDG drug targets, risk genes for complex traits in the GWAS catalog, and GO terms), for each of the three pairwise comparisons (A—SEM vs. teratoma, B—N-SEM vs. teratoma, C—SEM vs. N-SEM). Positive values indicate enrichment in the first histology group (A: SEM, B: N-SEM, C: SEM), and negative values indicate elevated expression in the second histology group (A: teratoma, B: teratoma, C: N-SEM).

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