Fig. 5 | Scientific Reports

Fig. 5

From: Comprehensive analysis of microRNA expression provides mechanistic insights into transcriptomic alteration in primary and metastatic testicular germ cell tumors

Fig. 5

Subgroup analysis in teratoma reveals minimal miRNA expression differences between tissue source and treatment groups. (A) Volcano plot showing the log2 fold-change (x-axis) between orchiectomy and RPLND samples, and the −log10 p-value of each miRNA (y-axis). (B) Volcano plot showing the log2 fold-change (x-axis) between chemotherapy-treated and chemotherapy-naive samples, and the −log10 p-value of each miRNA (y-axis). Differentially expressed miRNAs were identified by Bonferroni-adjusted p < 0.05 with log2 fold-change > 2. Previously described miRNAs implicated in TGCT are labeled.

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