Fig. 5 | Scientific Reports

Fig. 5

From: Comprehensive analysis of microRNA expression provides mechanistic insights into transcriptomic alteration in primary and metastatic testicular germ cell tumors

Fig. 5The alternative text for this image may have been generated using AI.

Subgroup analysis in teratoma reveals minimal miRNA expression differences between tissue source and treatment groups. (A) Volcano plot showing the log2 fold-change (x-axis) between orchiectomy and RPLND samples, and the −log10 p-value of each miRNA (y-axis). (B) Volcano plot showing the log2 fold-change (x-axis) between chemotherapy-treated and chemotherapy-naive samples, and the −log10 p-value of each miRNA (y-axis). Differentially expressed miRNAs were identified by Bonferroni-adjusted p < 0.05 with log2 fold-change > 2. Previously described miRNAs implicated in TGCT are labeled.

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