Fig. 6

Multi-disease comparison and SVM model. (A) Volcano plot of differentially abundant proteins between MIS-C and Kawasaki disease (K), pneumonia (P), and mild/asymptomatic SARS-CoV-2 (M/A). Proteins are depicted as green, red, or orange circles, based on Holm adjusted p value and fold-change, as in Fig. 2. (B) ROC curve visualizing the performance of a 3-protein signature (VWF, FCGBP, and SERPINA3). K Kawasaki disease, P pneumonia, M/A mild/asymptomatic SARS-CoV-2 infection.