Table 5 Antimicrobial stewardship strategies.

From: Implementation of infection prevention and control components in Italian hospitals based on a nationwide survey on behalf of INSIEME project

Variable

Core component 4: Antimicrobial stewardship

Antibiotic appropriateness evaluation

Empiric therapy protocols based on local epidemiology

Antibiotic restriction policy (any class)

Absent

(N = 10)

Present

(N = 28)

p valuea

Absent

(N = 22)

Present

(N = 16)

p valuea

Absent

(N = 12)

Present

(N = 26)

p valuea

Geographical area

Central Italy

2 (20.0%)

7 (25.0%)

0.327

4 (18.2%)

5 (31.25%)

0.416

1 (8.3%)

8 (30.8%)

0.192

Islands

3 (30.0%)

6 (21.4%)

 

7 (31.8%)

2 (12.5%)

 

2 (16.7%)

7 (26.9%)

 

Northern Italy

1 (10.0%)

10 (35.7%)

 

5 (22.7%)

6 (37.5%)

 

6 (50.0%)

5 (19.2%)

 

Southern Italy

4 (40.0%)

5 (17.9%)

 

6 (27.3%)

3 (18.75%)

 

3 (25.0%)

6 (23.1%)

 

Hospital type

Other

6 (60.0%)

9 (32.1%)

0.489

1 (4.5%)

0 (0%)

0.13

2 (16.7%)

0 (0%)

0.158

Private-public

4 (40.0%)

16 (57.1%)

 

11 (50.0%)

4 (25.0%)

 

5 (41.7%)

10 (38.5%)

 

Public hospital

0 (0%)

1 (3.6%)

 

10 (45.5%)

10 (62.5%)

 

5 (41.7%)

15 (57.7%)

 

University hospital

0 (0%)

2 (7.1%)

 

0

(0%)

2 (12.5%)

 

0 (0%)

1 (3.8%)

 

Bed capacity

 < 200

2 (20.0%)

8 (28.6%)

0.113

2

(9.1%)

2 (12.5%)

0.407

1 (8.3%)

3 (11.5%)

0.501

 ≥ 1000

4 (40.0%)

14 (50.0%)

 

4 (18.2%)

6 (37.5%)

 

5 (41.7%)

5 (19.2%)

 

200–599

4 (40.0%)

2 (7.1%)

 

11 (50.0%)

7 (43.75%)

 

4 (33.3%)

14 (53.8%)

 

600–999

0 (0%)

4 (14.3%)

 

5 (22.7%)

1 (6.25%)

 

2 (16.7%)

4 (15.4%)

 

Case-mix complexityb

High

4 (40.0%)

9 (32.1%)

1

7 (31.8%)

6 (37.5%)

0.323

6 (50.0%)

7 (26.9%)

0.383

Low

3 (30.0%)

10 (35.7%)

 

6 (27.3%)

7 (43.75%)

 

4 (33.3%)

9 (34.6%)

 

Medium

3 (30.0%)

9 (32.1%)

 

9 (40.9%)

3 (18.75%)

 

2 (16.7%)

10 (38.5%)

 
  1. aThe p-value is derived from the chi-squared test or, when expected cell counts are less than 5, from Fisher’s exact test.
  2. bsee text for details.