Table 2 Behavioural items recorded after the end of the procedure (Post MI). The score was obtained at multiple evaluations, starting from extubation until 12 h after sternal recumbency.

From: Unravelling pain in Göttingen Minipigs undergoing experimentally induced closed-chest myocardial infarction: a prospective cohort study

 

Appearance**

Lying and restlessness

**

Tremors/ Spasms

Vocalisation

Food interest

Agitation at

human approaching

*

Response to touch (neck, head, thorax and forelimbs)

*

0

Normal appearance

Normal lying

No evidence

of tremors/

spasms

No vocalisation or vocalisation related to food/interest in human/mate approach

Normal appetite

Curious, interactive, may vocalise

No response

1

Salivation

Lying guarding one part of the body/moves without external stimulation

Tremors/ spasms in one part of the body

Vocalisation without a purpose/ unmotivated excitation

Reduced appetite, eat special/ tasty food

Moves away when approached

Mild response: the animal looks uncomfortable and worried; retraction of the interested body part can be present

2

//

Move often/ poor wake times

Generalised tremors/

spasms

//

Reduced appetite independently of the food

Biting and aggressive when approached

Severe response: escape reaction

3

//

Continuous pacing in the box

 

//

No appetite

Stay immobile and disinterested

//

  1. ** items not assessed at extubation and sternal recumbency; * items not assessed at extubation.