Fig. 6 | Scientific Reports

Fig. 6

From: The impact of Streptococcus thermophilus IDCC 2201 on gut microbiota and its potential as a prophylactic agent for colorectal cancer

Fig. 6

Inhibition of cancer cell viability by S. thermophilus-derived folate. (A and B) Viability of cancer cell lines, HCT116 (A) and HT-29 (B), with the treatment of 20% (v/v) culture supernatant of E. coli (ECO) and S. thermophilus (STH) compared to medium. (C-F) Viability of cancer cell lines, HCT116 (C and D) and HT-29 (E and F), with the treatment of culture supernatant of S. thermophilus (STH), pyridoxine (B6), folate (B9), and 5-fluorouracil (5-FU) compared to DPBS control. The culture supernatant of S. thermophilus was prepared with the para-aminobenzoic acid (pABA)-rich and -deficient media (D and F). Significant differences are indicated by asterisks at the 95% (*), 99% (**), 99.9% (***), and 99.99% (****) significance levels using one-way ANOVA with Dunnett’s post-hoc analysis.

Back to article page