Fig. 4 | Scientific Reports

Fig. 4

From: Research on the potential mechanisms and therapeutic drug for the co-occurrence of major depressive disorder in castration-resistant prostate cancer

Fig. 4

Identification and validation of hub genes. (A) LASSO, SVM, and RF algorithm for CRPC. (B) LASSO, SVM, and RF algorithm for MDD. (C) Three hub genes were obtained after overlapping machine learning algorithms. (D) SHAP interpretation of model for CRPC. (E) SHAP interpretation of model for MDD. (F) ROC curve of hub genes in the internal and external dataset of CRPC. (G) ROC curve of hub genes in the internal and external dataset of MDD. (H) Decision curve analysis of CRPC. (I) Decision curve analysis of MDD. (J) Survival curves of hub genes in CRPC.

Back to article page