Fig. 7

Tumor growth rate. Tumor volumes of the differentially immunized mice were monitored. Tumor volumes of individual mice in empty LNP, OVA mRNA, FljB mRNA/OVA mRNA, and FljB-OVA mRNA groups were shown in A-D, respectively. Overall tumor growth was summarized in E. Dashed line: 25% of tumor volume of empty LNP group on day 20. Two-way ANOVA with Dunnett’s multiple comparisons test was used to compare differences between groups in E. n = 5. *, p < 0.05; ***, p < 0.001.