Fig. 9
(A, B) Development and performance of the combined model. (A) Correlation matrix for combined features. Test of mutual correlation with Spearman. The Spearman correlation coefficient is color-coded: blue indicates a positive correlation, whereas red represents a negative correlation. The intensity of the color reflects the strength of the correlation. CRP: C-reactive protein; Pmean: mean airway pressure; PEEP: positive end expiratory pressure. (B) Performance of the combined model. The ROC curve for the Combined Model in the training cohort (blue) had an AUROC of 0.842. The optimal threshold for the combined model was determined via the Youden index, which yielded a value of 0.304. The performance of the Clinical Model in the validation cohort (red) resulted in an AUROC of 0.705.
