Table 3 Cox-proportional hazard models for the association of TyG and the combined indices with stroke risk.
Case | Model 1 HR (95% CI) P value | Model 2 HR (95% CI) P value | Model 3 HR (95% CI) P value | |
|---|---|---|---|---|
TyG | ||||
TyG Per-SD | 1.23 (1.14, 1.34) < 0.001 | 1.25 (1.15, 1.36) < 0.001 | 1.25 (1.08, 1.44) 0.003 | |
TyG quartile | ||||
Q1(≤ 8.22) | 77(3.54%) | Ref | Ref | Ref |
Q2(8.22–8.60) | 108(4.94%) | 1.40 (1.05, 1.88) 0.024 | 1.44 (1.07, 1.93) 0.015 | 1.33 (0.94, 1.90) 0.108 |
Q3(8.60–9.05) | 135(6.18%) | 1.75 (1.32, 2.32) < 0.001 | 1.77 (1.34, 2.35) < 0.001 | 1.67 (1.18, 2.37) 0.004 |
Q4(≥ 9.05) | 136(6.23%) | 1.79 (1.36, 2.37) < 0.001 | 1.87 (1.41, 2.49) < 0.001 | 1.45 (0.98, 2.16) 0.046 |
TyG-BMI | ||||
TyG-BMI Per-SD | 1.23 (1.14, 1.33) < 0.001 | 1.29 (1.19, 1.39) < 0.001 | 1.18 (1.05, 1.32) 0.005 | |
TyG-BMI quartile | ||||
Q1(≤ 175.24) | 78(3.57%) | Ref | Ref | Ref |
Q2(175.25-198.84) | 107(4.90%) | 1.38 (1.03, 1.85) 0.029 | 1.54 (1.14, 2.06) 0.004 | 1.59 (1.12, 2.25) 0.009 |
Q3(198.84-228.85) | 119(5.45%) | 1.52 (1.14, 2.02) 0.004 | 1.77 (1.32, 2.36) 0.0001 | 1.60 (1.11, 2.29) 0.011 |
Q4(≥ 228.86) | 152(6.96%) | 1.95 (1.49, 2.57) < 0.001 | 2.37 (1.79, 3.15) < 0.001 | 1.85 (1.26, 2.71) 0.002 |
TyG-WC | ||||
TyG-WC Per-SD | 1.34 (1.22, 1.46) < 0.001 | 1.35 (1.23, 1.48) < 0.001 | 1.22 (1.07, 1.40) 0.003 | |
TyG-WC quartile | ||||
Q1(≤ 649.76) | 76(3.48%) | Ref | Ref | Ref |
Q2(649.79-725.39) | 99(4.54%) | 1.31 (0.97, 1.77) 0.075 | 1.32 (0.98, 1.79) 0.067 | 1.37 (0.96, 1.97) 0.081 |
Q3(725.41-815.48) | 121(5.35%) | 1.62 (1.21, 2.15) 0.001 | 1.66 (1.24, 2.21) 0.0006 | 1.60 (1.12, 2.28) 0.009 |
Q4(≥ 815.51) | 160(7.55%) | 2.13 (1.62, 2.80) < 0.001 | 2.19 (1.66, 2.88) < 0.001 | 1.85 (1.27, 2.70) 0.001 |
TyG-WHtR | ||||
TyG-WHtR Per-SD | 1.31 (1.20, 1.44) < 0.001 | 1.34 (1.21, 1.47) < 0.001 | 1.19 (1.04, 1.36) 0.009 | |
TyG-WHtR quartile | ||||
Q1(≤ 4.10) | 78(3.57%) | Ref | Ref | Ref |
Q2(4.10–4.61) | 91(4.17%) | 1.17 (0.87, 1.59) 0.301 | 1.21 (0.90, 1.65) 0.211 | 1.27 (0.89, 1.81) 0.194 |
Q3(4.61–5.18) | 128(5.87%) | 1.65 (1.24, 2.18) < 0.001 | 1.74 (1.31, 2.32) < 0.001 | 1.46 (1.03, 2.09) 0.035 |
Q4(≥ 5.18) | 159(7.28%) | 2.07 (1.58, 2.71) < 0.001 | 2.22 (1.67, 2.95) < 0.001 | 1.89 (1.29, 2.77) 0.001 |
TyG-WWI | ||||
TyG-WWI Per-SD | 1.28 (1.16, 1.42) < 0.001 | 1.26 (1.13, 1.40) < 0.001 | 1.14 (0.99, 1.31) 0.063 | |
TyG-WWI quartile | ||||
Q1(≤ 88.56) | 76(3.48%) | Ref | Ref | Ref |
Q2(88.57–95.86) | 106(4.86%) | 1.42 (1.06, 1.91) 0.019 | 1.39 (1.03, 1.86) 0.030 | 1.23 (0.87, 1.75) 0.243 |
Q3(95.87-103.96) | 125(5.73%) | 1.65 (1.24, 2.20) < 0.001 | 1.63 (1.22, 2.18) 0.001 | 1.43 (1.01, 2.03) 0.045 |
Q4(≥ 104.01) | 149(6.83%) | 2.01 (1.53, 2.65) < 0.001 | 1.94 (1.45, 2.60) < 0.001 | 1.50 (1.02, 2.21) 0.041 |
TyG-ABSI | ||||
TyG-ABSI Per-SD | 1.27 (1.14, 1.40) < 0.001 | 1.21 (1.09, 1.34) < 0.001 | 1.12 (0.98, 1.27) 0.099 | |
TyG-ABSI quartile | ||||
Q1(≤ 0.67) | 81(3.71%) | Ref | Ref | Ref |
Q2(0.67–0.71) | 111(5.09%) | 1.39 (1.04, 1.85) 0.024 | 1.33 (1.00, 1.77) 0.053 | 1.33 (0.94, 1.89) 0.105 |
Q3(0.71–0.77) | 113(5.18%) | 1.40 (1.06, 1.87) 0.019 | 1.29 (0.96, 1.72) 0.087 | 1.30 (0.92, 1.85) 0.047 |
Q4(≥ 0.77) | 151(6.92%) | 1.92 (1.47, 2.52) < 0.001 | 1.71 (1.29, 2.26) < 0.001 | 1.45 (1.01, 2.11) 0.034 |
TyG-BRI | ||||
TyG-BRI Per-SD | 1.28 (1.18, 1.40) < 0.001 | 1.30 (1.19, 1.43) < 0.001 | 1.15 (1.02, 1.29) 0.019 | |
TyG-BRI quartile | ||||
Q1(≤ 26.65) | 79(3.62%) | Ref | Ref | Ref |
Q2(26.66–34.72) | 89(4.08%) | 1.12 (0.83, 1.52) 0.447 | 1.16 (0.86, 1.58) 0.334 | 1.19 (0.83, 1.70) 0.339 |
Q3(34.72–44.91) | 127(5.82%) | 1.61 (1.21, 2.13) < 0.001 | 1.72 (1.29, 2.30) < 0.001 | 1.50 (1.05, 2.13) 0.024 |
Q4(≥ 44.91) | 161(7.38%) | 2.06 (1.57, 2.69) < 0.001 | 2.24 (1.68, 2.97) < 0.001 | 1.87 (1.29, 2.70) < 0.001 |