Table 2 Medication histories within six months before conception in the experimental and control groups for each outcome.

From: Risk factors of adverse pregnancy outcomes in patients with immunoglobulin A nephropathy

 

Hypertensive disorders of pregnancy (required intravenous nicardipine)

Preterm delivery (delivered before 37 weeks of pregnancy)

Pregnancies, n (%)

Odds ratios (95%CI)

Pregnancies, n (%)

Odds ratios (95%CI)

Case

Control

Crude

Adjusted

Case

Control

Crude

Adjusted

34 (100%)

263 (100%)

  

56 (100%)

237 (100%)

  

Antihypertensive medications within six months before conception

 All categories

9 (26.5%)

35 (13.3%)

2.35 (1.01–5.44)

2.13 a (0.91–5.01)

15 (26.8%)

26 (11.0%)

2.97 (1.45–6.09)

3.02 b (1.43–6.39)

 Only RASi e

4 (11.8%)

28 (10.6%)

1.30 (0.42–4.02)

1.27 a (0.41–3.96)

9 (16.1%)

21 (8.9%)

2.21 (0.94–5.16)

2.17 b (0.88–5.32)

 Medications other than RASi e

5 (14.7%)

7 (2.7%)

6.51 (1.92–22.1)

5.01 a (1.43–17.5)

6 (10.7%)

5 (2.1%)

6.18 (1.80–21.2)

6.45 b (1.81–23.0)

Glucocorticoid therapy within six months before conception

 All (DIV or PO)

4 (11.8%)

29 (11.0%)

1.08 (0.35–3.27)

1.09 c (0.35–3.45)

6 (10.7%)

27 (11.4%)

0.93 (0.37–2.38)

0.84 d (0.31–2.32)

 DIV e

1 (2.9%)

7 (2.7%)

1.11 (0.13–9.29)

1.84 c (0.21–16.5)

1 (1.8%)

7 (3.0%)

0.60 (0.07–4.96)

1.23 d (0.14–10.7)

 PO e

4 (11.8%)

28 (10.6%)

1.12 (0.37–3.41)

1.14 c (0.36–3.61)

6 (10.7%)

26 (11.0%)

0.97 (0.38–2.49)

0.87 d (0.31–2.42)

  1. CI confidence interval, RASi renin–angiotensin–aldosterone system inhibitors, DIV drip in vein, PO per os. Bold values indicate statistical significance (P < 0.05).
  2. a Odds ratios adjusted for age, smoking history, and diabetes mellitus (DM).
  3. b Odds ratios adjusted for age, smoking history, DM, and chorioamnionitis (CAM).
  4. c Odds ratios adjusted for age, smoking history, DM, and hypertension (HT).
  5. d Odds ratios adjusted for age, smoking history, DM, HT, and CAM.
  6. e Details of medications are shown in Table S1.